Mario Saltarelli, M.D., Ph.D.


Mario Saltarelli

Dr. Mario Saltarelli is the former executive vice president and chief medical officer of Syntimmune. Following the recent acquisition of Syntimmune by Alexion, Dr. Saltarelli is supporting the transition of Syntimmune’s development activities as a member of Alexion’s Medical Sciences organization. Previously, Dr. Saltarelli was the senior vice president of early development and neurology at Vertex Pharmaceuticals Incorporated. At Vertex, he led the company’s early development activities, including translational medicine, clinical pharmacology, clinical biomarkers and neurology. For more than 20 years, Dr. Saltarelli has been focused on defining, building and successfully advancing development pipelines through the application of advanced translational paradigms in the biomedical and pharmaceutical sectors.

Prior to joining Vertex, Dr. Saltarelli served as chief medical officer at Annexon Biosciences, Inc. and served as the chief science officer and senior vice president of Mallinckrodt. Dr. Saltarelli served as senior vice president of clinical development and medical affairs at Shire. His diverse background spans more than three decades across medical science, clinical drug development and the scientific and regulatory aspects of clinical program design. He joined Shire from Abbott Laboratories where he served as the divisional vice president directly accountable for all aspects of clinical development, medical affairs and development strategy for global neuroscience and anesthesia products. Prior to that, he spent seven years at Pfizer global research and development in Connecticut, ultimately as an executive director, head of the CNS early clinical development group. He served as director of MindImmune Therapeutics. He served for four years as an assistant professor of neurology at Emory University School of Medicine.

Dr. Saltarelli earned his bachelor of science degree in psychology from the University of Illinois at Urbana-Champaign, a doctor of medicine degree and a doctor of philosophy degree in neuropharmacology from The Johns Hopkins University School of Medicine. He was an intern in internal medicine at the University of Maryland Medical Center and completed neurology residency at The Johns Hopkins Hospital.